EUTECNIQ Sciences

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Academy Primary sources Published evidence Calculators

Twelve courses on how a plant becomes a documented ingredient, with the equations, data and rules shown

The science a botanical ingredient depends on, from where the plant grew to what its label may say. Each course states the principle, shows the measurement, works a published example and names the limits.

Structure
Six question stages and one course that weighs them together
Sources
Statutes, FDA, USP, ICH, OECD, EFSA and peer-reviewed papers
Cost
Free, no registration
12courses, from where a plant grows to what its label may say
190figures, from heat maps to rotating 3D molecules
29calculators and explorers you can use
603numbers, dates and rules registered with their source
463references to statutes, guidelines and papers
Find a course

Twelve courses answer the six questions a product meets, and Course 11 weighs the answers together

The Academy by question stage: select a stage to zoom in, or a course to open itNavigation map
One segment per course; segment size carries no data. Stages as in the curriculum figure below; Course 11 (Decision) draws on all six.

Scope. Education, not medical, legal or regulatory advice; nothing here recommends a dose or a product. EUTECNIQ is a company in formation with no laboratory or results; each course marks its proposals in a labeled box.

Curriculum

One ingredient decision draws on twelve disciplines, so the courses follow the questions in the order a product meets them

The twelve courses placed on the plant-to-product questions they answerCourse structure
Curriculum map: the twelve Academy courses placed on the plant-to-product questions they answer. Origin: courses 1, 2 and 5. Identity: 3 and 4. Composition: 6, 7 and 12. In the body: 8. Safety: 9. Claims: 10. Course 11, multi-objective ingredient design, integrates all six columns into one decision.OriginWhere does it comefrom?IdentityWhat exactly is it?CompositionWhat is in it, and whatmust not be?In the bodyDoes it dissolve and getabsorbed?SafetyAt what intake is it safe?ClaimsWhat may the labelsay?Course 1: History of botanical medicine1History ofbotanicalmedicineHow culturesrecorded plantmedicines, andwhich becamedrugsCourse 2: The untapped botanicals2The untappedbotanicalsWhy mostmedicinal plantsnever reach a U.S.productCourse 5: Soil and cultivation5Soil andcultivationHow soil, climateand harvestchange chemistryand metalsCourse 3: Botanical identity3Botanical identityNames,microscopy,HPTLC and DNAbarcodesCourse 4: Genomes and species4Genomes andspeciesGenome size,polyploidy and thegenes behindcompoundsCourse 6: Certificate-of-analysis science6Certificate-of-analysis scienceMetals, solvents,pesticides andmycotoxins againstICH and USP limitsCourse 7: Microbiology of botanicals7Microbiology ofbotanicalsUSP microbialtests, spores,biofilms andnonculturable cellsCourse 12: Other ingredients and excipients12Other ingredientsand excipientsFillers, carriers andflow agents: theirjobs, legal routesand label linesCourse 8: Solubility, pH and the body8Solubility, pHand the bodypH along the gut,dose number anddose-dependentexposureCourse 9: Toxicology and dose9Toxicology anddoseFrom LD50 andNOAEL to a safedaily intakeCourse 10: Why no disease claims10Why no diseaseclaimsDSHEA, 21 CFR101.93 and thebotanical drugroute11Multi-objective ingredient designWeighs every column at once: quality, bioavailability, safety, regulatory status, supply and scale, with hard limits as gatesCurriculum map (phone layout): six question stages with their courses, and Course 11 integrating them.OriginWhere does it come from?1History of botanical medicineHow cultures recorded plant medicines, and whichbecame drugs2The untapped botanicalsWhy most medicinal plants never reach a U.S.product5Soil and cultivationHow soil, climate and harvest change chemistryand metalsIdentityWhat exactly is it?3Botanical identityNames, microscopy, HPTLC and DNA barcodes4Genomes and speciesGenome size, polyploidy and the genes behindcompoundsCompositionWhat is in it, and what must not be?6Certificate-of-analysis scienceMetals, solvents, pesticides and mycotoxinsagainst ICH and USP limits7Microbiology of botanicalsUSP microbial tests, spores, biofilms andnonculturable cells12Other ingredients and excipientsFillers, carriers and flow agents: their jobs, legalroutes and label linesIn the bodyDoes it dissolve and get absorbed?8Solubility, pH and the bodypH along the gut, dose number anddose-dependent exposureSafetyAt what intake is it safe?9Toxicology and doseFrom LD50 and NOAEL to a safe daily intakeClaimsWhat may the label say?10Why no disease claimsDSHEA, 21 CFR 101.93 and the botanical drug route11Multi-objective ingredient designWeighs every column at once: quality, bioavailability,safety, regulatory status, supply and scale, with hardlimits as gates
Course numbers follow the reading order in the navigation menu.
Explanation, details and sources

Eleven courses each answer one question about a botanical or the product it goes into. Course 11 shows how those answers are weighed together, with legal and safety limits treated as gates rather than as trade-offs.

Course catalog

Each course teaches the principle, the measurement, a worked example and the limits

What each course contains: figures, interactive tools, registered claims and referencesCounted from the pages
Course contents counted from the course pages: 190 figures, 29 interactive tools, 603 registered claims and 463 references across twelve courses. Course 1: 18 figures, 1 tools, 64 claims, 78 references. Course 2: 16 figures, 2 tools, 38 claims, 28 references. Course 3: 15 figures, 2 tools, 60 claims, 39 references. Course 4: 14 figures, 2 tools, 51 claims, 45 references. Course 5: 16 figures, 2 tools, 52 claims, 29 references. Course 6: 20 figures, 4 tools, 71 claims, 24 references. Course 7: 16 figures, 4 tools, 52 claims, 44 references. Course 8: 15 figures, 3 tools, 53 claims, 55 references. Course 9: 17 figures, 3 tools, 60 claims, 49 references. Course 10: 16 figures, 2 tools, 28 claims, 23 references. Course 11: 13 figures, 2 tools, 29 claims, 27 references. Course 12: 14 figures, 2 tools, 45 claims, 22 references.FiguresTotal 190Course 1, History of botanical medicine: 18 figures18Course 2, The untapped botanicals: 16 figures16Course 3, Botanical identity: 15 figures15Course 4, Genomes and species: 14 figures14Course 5, Soil and cultivation: 16 figures16Course 6, Certificate-of-analysis science: 20 figures20Course 7, Microbiology of botanicals: 16 figures16Course 8, Solubility, pH and the body: 15 figures15Course 9, Toxicology and dose: 17 figures17Course 10, Why no disease claims: 16 figures16Course 11, Multi-objective ingredient design: 13 figures13Course 12, Other ingredients and excipients: 14 figures14Interactive toolsTotal 29Course 1, History of botanical medicine: 1 interactive tools1Course 2, The untapped botanicals: 2 interactive tools2Course 3, Botanical identity: 2 interactive tools2Course 4, Genomes and species: 2 interactive tools2Course 5, Soil and cultivation: 2 interactive tools2Course 6, Certificate-of-analysis science: 4 interactive tools4Course 7, Microbiology of botanicals: 4 interactive tools4Course 8, Solubility, pH and the body: 3 interactive tools3Course 9, Toxicology and dose: 3 interactive tools3Course 10, Why no disease claims: 2 interactive tools2Course 11, Multi-objective ingredient design: 2 interactive tools2Course 12, Other ingredients and excipients: 2 interactive tools2Registered claimsTotal 603Course 1, History of botanical medicine: 64 registered claims64Course 2, The untapped botanicals: 38 registered claims38Course 3, Botanical identity: 60 registered claims60Course 4, Genomes and species: 51 registered claims51Course 5, Soil and cultivation: 52 registered claims52Course 6, Certificate-of-analysis science: 71 registered claims71Course 7, Microbiology of botanicals: 52 registered claims52Course 8, Solubility, pH and the body: 53 registered claims53Course 9, Toxicology and dose: 60 registered claims60Course 10, Why no disease claims: 28 registered claims28Course 11, Multi-objective ingredient design: 29 registered claims29Course 12, Other ingredients and excipients: 45 registered claims45ReferencesTotal 463Course 1, History of botanical medicine: 78 references78Course 2, The untapped botanicals: 28 references28Course 3, Botanical identity: 39 references39Course 4, Genomes and species: 45 references45Course 5, Soil and cultivation: 29 references29Course 6, Certificate-of-analysis science: 24 references24Course 7, Microbiology of botanicals: 44 references44Course 8, Solubility, pH and the body: 55 references55Course 9, Toxicology and dose: 49 references49Course 10, Why no disease claims: 23 references23Course 11, Multi-objective ingredient design: 27 references27Course 12, Other ingredients and excipients: 22 references221 History of botanical medicine2 The untapped botanicals3 Botanical identity4 Genomes and species5 Soil and cultivation6 Certificate-of-analysis science7 Microbiology of botanicals8 Solubility, pH and the body9 Toxicology and dose10 Why no disease claims11 Multi-objective ingredient design12 Other ingredients and excipients
Counted from each course's page source, claims.json and refs.json when the site is built. A tool is a calculator or explorer with a Reset control. A registered claim is a number, date or rule recorded with its source and verification date.
Course 2 · Origin

The untapped botanicals

Why few medicinal plants have the evidence a U.S. product needs.

The evidence funnel →
Course 3 · Identity

Botanical identity

Names, plant parts, microscopy, HPTLC and DNA barcodes.

Identity methods →
Course 4 · Identity

Genomes and species

Genome size, polyploidy and the genes behind compounds.

Genomes →
Course 5 · Origin

Soil and cultivation

How soil, climate and harvest change chemistry and metals.

Soil to extract →
Course 7 · Composition

Microbiology of botanicals

USP microbial tests, spores, biofilms and cells plate counts miss.

Microbiology →
Course 9 · Safety

Toxicology and dose

LD50, NOAEL, benchmark dose and margins of exposure.

Toxicology →
Course 10 · Claims

Why no disease claims

The line between a structure/function claim and a drug claim.

Claims →
Reading paths

Start with the courses that answer your role's first question

Suggested starting points and next courses by roleEditorial suggestion
Suggested reading paths: for each role, courses to start with, courses recommended next, and optional courses. Investor or board member: start with 2 Untapped, 10 Claims, 11 Design. Brand or product developer: start with 6 COA, 8 Solubility, 10 Claims, 12 Excipients. Quality and supplier qualification: start with 3 Identity, 5 Soil, 6 COA, 7 Microbes, 12 Excipients. Regulatory and claims: start with 2 Untapped, 9 Toxicology, 10 Claims. Scientist or student: start with 1 History, 3 Identity, 4 Genomes, 8 Solubility, 9 Toxicology, 11 Design.1History2Untapped3Identity4Genomes5Soil6COA7Microbes8Solubility9Toxicology10Claims11Design12ExcipientsInvestor or board memberInvestor or board member · 1 History: mediumInvestor or board member · 2 Untapped: highInvestor or board member · 3 Identity: lowInvestor or board member · 4 Genomes: lowInvestor or board member · 5 Soil: lowInvestor or board member · 6 COA: mediumInvestor or board member · 7 Microbes: lowInvestor or board member · 8 Solubility: lowInvestor or board member · 9 Toxicology: mediumInvestor or board member · 10 Claims: highInvestor or board member · 11 Design: highInvestor or board member · 12 Excipients: lowBrand or product developerBrand or product developer · 1 History: lowBrand or product developer · 2 Untapped: mediumBrand or product developer · 3 Identity: mediumBrand or product developer · 4 Genomes: lowBrand or product developer · 5 Soil: lowBrand or product developer · 6 COA: highBrand or product developer · 7 Microbes: mediumBrand or product developer · 8 Solubility: highBrand or product developer · 9 Toxicology: mediumBrand or product developer · 10 Claims: highBrand or product developer · 11 Design: mediumBrand or product developer · 12 Excipients: highQuality and supplier qualificationQuality and supplier qualification · 2 Untapped: lowQuality and supplier qualification · 3 Identity: highQuality and supplier qualification · 4 Genomes: mediumQuality and supplier qualification · 5 Soil: highQuality and supplier qualification · 6 COA: highQuality and supplier qualification · 7 Microbes: highQuality and supplier qualification · 8 Solubility: lowQuality and supplier qualification · 9 Toxicology: mediumQuality and supplier qualification · 10 Claims: lowQuality and supplier qualification · 11 Design: lowQuality and supplier qualification · 12 Excipients: highRegulatory and claimsRegulatory and claims · 1 History: lowRegulatory and claims · 2 Untapped: highRegulatory and claims · 3 Identity: mediumRegulatory and claims · 5 Soil: lowRegulatory and claims · 6 COA: mediumRegulatory and claims · 7 Microbes: lowRegulatory and claims · 8 Solubility: lowRegulatory and claims · 9 Toxicology: highRegulatory and claims · 10 Claims: highRegulatory and claims · 11 Design: lowRegulatory and claims · 12 Excipients: mediumScientist or studentScientist or student · 1 History: highScientist or student · 2 Untapped: mediumScientist or student · 3 Identity: highScientist or student · 4 Genomes: highScientist or student · 5 Soil: mediumScientist or student · 6 COA: mediumScientist or student · 7 Microbes: mediumScientist or student · 8 Solubility: highScientist or student · 9 Toxicology: highScientist or student · 10 Claims: mediumScientist or student · 11 Design: highScientist or student · 12 Excipients: mediumStart hereRecommended nextOptionalNot needed for this role
EUTECNIQ editorial suggestion. Every course stands on its own.
How the courses are built

Every number is registered with its source and evidence label, and every calculator is checked against independent code

Most registered claims rest on regulations, agency guidance, primary data or peer-reviewed papersCounted from the pages
Registered claims by course and evidence label: 603 claims, 579 with status verified and 24 qualified. Regulation or agency guidance: 169. Government or primary data: 187. Peer-reviewed evidence: 206. Educational model output: 26. Proposal or third-party estimate: 15.Registered claims, by evidence labelStatus verified1 History of botanical medicineCourse 1, History of botanical medicine: 5 of 64 claims, regulation or agency guidanceCourse 1, History of botanical medicine: 25 of 64 claims, government or primary dataCourse 1, History of botanical medicine: 32 of 64 claims, peer-reviewed evidenceCourse 1, History of botanical medicine: 1 of 64 claims, educational model outputCourse 1, History of botanical medicine: 1 of 64 claims, proposal or third-party estimate6460 of 642 The untapped botanicalsCourse 2, The untapped botanicals: 7 of 38 claims, regulation or agency guidanceCourse 2, The untapped botanicals: 23 of 38 claims, government or primary dataCourse 2, The untapped botanicals: 5 of 38 claims, peer-reviewed evidenceCourse 2, The untapped botanicals: 2 of 38 claims, educational model outputCourse 2, The untapped botanicals: 1 of 38 claims, proposal or third-party estimate3837 of 383 Botanical identityCourse 3, Botanical identity: 10 of 60 claims, regulation or agency guidanceCourse 3, Botanical identity: 21 of 60 claims, government or primary dataCourse 3, Botanical identity: 25 of 60 claims, peer-reviewed evidenceCourse 3, Botanical identity: 3 of 60 claims, educational model outputCourse 3, Botanical identity: 1 of 60 claims, proposal or third-party estimate6059 of 604 Genomes and speciesCourse 4, Genomes and species: 3 of 51 claims, regulation or agency guidanceCourse 4, Genomes and species: 7 of 51 claims, government or primary dataCourse 4, Genomes and species: 37 of 51 claims, peer-reviewed evidenceCourse 4, Genomes and species: 3 of 51 claims, educational model outputCourse 4, Genomes and species: 1 of 51 claims, proposal or third-party estimate5150 of 515 Soil and cultivationCourse 5, Soil and cultivation: 10 of 52 claims, regulation or agency guidanceCourse 5, Soil and cultivation: 7 of 52 claims, government or primary dataCourse 5, Soil and cultivation: 32 of 52 claims, peer-reviewed evidenceCourse 5, Soil and cultivation: 2 of 52 claims, educational model outputCourse 5, Soil and cultivation: 1 of 52 claims, proposal or third-party estimate5252 of 526 Certificate-of-analysis scienceCourse 6, Certificate-of-analysis science: 44 of 71 claims, regulation or agency guidanceCourse 6, Certificate-of-analysis science: 21 of 71 claims, government or primary dataCourse 6, Certificate-of-analysis science: 3 of 71 claims, educational model outputCourse 6, Certificate-of-analysis science: 3 of 71 claims, proposal or third-party estimate7164 of 717 Microbiology of botanicalsCourse 7, Microbiology of botanicals: 6 of 52 claims, regulation or agency guidanceCourse 7, Microbiology of botanicals: 23 of 52 claims, government or primary dataCourse 7, Microbiology of botanicals: 20 of 52 claims, peer-reviewed evidenceCourse 7, Microbiology of botanicals: 1 of 52 claims, educational model outputCourse 7, Microbiology of botanicals: 2 of 52 claims, proposal or third-party estimate5248 of 528 Solubility, pH and the bodyCourse 8, Solubility, pH and the body: 3 of 53 claims, regulation or agency guidanceCourse 8, Solubility, pH and the body: 9 of 53 claims, government or primary dataCourse 8, Solubility, pH and the body: 37 of 53 claims, peer-reviewed evidenceCourse 8, Solubility, pH and the body: 3 of 53 claims, educational model outputCourse 8, Solubility, pH and the body: 1 of 53 claims, proposal or third-party estimate5352 of 539 Toxicology and doseCourse 9, Toxicology and dose: 23 of 60 claims, regulation or agency guidanceCourse 9, Toxicology and dose: 26 of 60 claims, government or primary dataCourse 9, Toxicology and dose: 5 of 60 claims, peer-reviewed evidenceCourse 9, Toxicology and dose: 4 of 60 claims, educational model outputCourse 9, Toxicology and dose: 2 of 60 claims, proposal or third-party estimate6059 of 6010 Why no disease claimsCourse 10, Why no disease claims: 17 of 28 claims, regulation or agency guidanceCourse 10, Why no disease claims: 10 of 28 claims, government or primary dataCourse 10, Why no disease claims: 1 of 28 claims, proposal or third-party estimate2828 of 2811 Multi-objective ingredient designCourse 11, Multi-objective ingredient design: 7 of 29 claims, regulation or agency guidanceCourse 11, Multi-objective ingredient design: 5 of 29 claims, government or primary dataCourse 11, Multi-objective ingredient design: 12 of 29 claims, peer-reviewed evidenceCourse 11, Multi-objective ingredient design: 4 of 29 claims, educational model outputCourse 11, Multi-objective ingredient design: 1 of 29 claims, proposal or third-party estimate2926 of 2912 Other ingredients and excipientsCourse 12, Other ingredients and excipients: 34 of 45 claims, regulation or agency guidanceCourse 12, Other ingredients and excipients: 10 of 45 claims, government or primary dataCourse 12, Other ingredients and excipients: 1 of 45 claims, peer-reviewed evidence4544 of 45Regulation or agency guidance (169)Government or primary data (187)Peer-reviewed evidence (206)Educational model output (26)Proposal or third-party estimate (15)
Counted from each course's claims.json when the site is built. A "qualified" claim carries a stated limitation, such as a secondary source or a text that could not be read in full. Full list of sources: Sources page.
Explanation, details and sources

Sources first. Limits, constants and dates come from the statute, the regulation, the pharmacopeia, the guideline or the peer-reviewed paper, cited where they are used. All sources are listed on the Sources page.

Labeled evidence. Each figure carries one evidence label: verified fact, published evidence, regulatory requirement, agency guidance, educational model or EUTECNIQ proposal.

Tested calculators. Each calculator states its equation, units, valid range and limits. Automated tests compare its output with a separate Python implementation and with published worked examples where they exist.

Why EUTECNIQ publishes this

The courses show the disciplines EUTECNIQ proposes to hold in one place

Start with Course 1

How plant records became testable hypotheses, and then medicines.

Begin the coursesSuggest a topic